Spectrum and Drug Sensitivity of Common Pathogens Causing Septicemia in Children
Objective: To investigate the spectrum and drug sensitivity of pathogenic bacteria in children presenting with septicemia.
Methods: A retrospective analysis was performed on the spectrum and drug sensitivity of pathogenic bacteria in 450 children (age0— 5 years) with septicemia, who were admitted from January to December, 2014.
Results: A total of 450 blood culture samples were collected. Out of these 30% were cultures positive. Gram negative bacteria were 63%of total isolates and gram positive were 37%.The commonest gram negative bacterial isolates were E Coli(22%) followed by Klebsiella (11%) , acintobacter (9%) , pseudomonas (8%) ,salmonella typhi (6%) ,salmonella paratyphi (4%) and hemophillus influenza type B(3%).Among the gram positive organisms commonest organisms were staphylococcus aureus (15%), staphylococcus epidermidis(10%) , methicillin resistant staphylococcus (MRSA) (7%) and pneummococcus (5%) .
Conclusion: E Coli was the most commonly isolated pathogen in pediatric age group less than 5 years sensitive to third generation cephalosporins and aminoglycosides(1).Commonest gram positive isolate was staphylococcus aureus which was sensitive to amoxicillin + clavulanic acid, aminoglycosides and vancomycin .
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