Spectrum and Drug Sensitivity of Common Pathogens Causing Septicemia in Children

  • MUHAMMAD RASHID AYUB, NABEELA RASHID, NAVEED AKBAR HOTIANA
Keywords: Septicemia, Escherichia coli (Ecoli), Klebsiella, Pseudomonas, MRSA

Abstract

Objective: To investigate the spectrum and drug sensitivity of pathogenic bacteria in children presenting with septicemia.

Methods: A retrospective analysis was performed on the spectrum and drug sensitivity of pathogenic bacteria in 450 children (age0— 5 years) with septicemia, who were admitted from January to December, 2014.

Results: A total of 450 blood culture samples were collected. Out of these 30% were cultures positive. Gram negative bacteria were 63%of total isolates and gram positive were 37%.The commonest gram negative bacterial isolates were E Coli(22%) followed by Klebsiella (11%) , acintobacter (9%) , pseudomonas (8%) ,salmonella typhi (6%) ,salmonella paratyphi (4%) and hemophillus influenza type B(3%).Among the gram positive organisms commonest organisms were staphylococcus aureus (15%), staphylococcus epidermidis(10%) , methicillin resistant staphylococcus (MRSA) (7%) and pneummococcus (5%) .

Conclusion: E Coli was the most commonly isolated pathogen in pediatric age group less than 5 years sensitive to third generation cephalosporins and aminoglycosides(1).Commonest gram positive isolate was staphylococcus aureus which was sensitive to amoxicillin + clavulanic acid, aminoglycosides and vancomycin .

Published
2018-11-22
How to Cite
1.
NAVEED AKBAR HOTIANA MRANR. Spectrum and Drug Sensitivity of Common Pathogens Causing Septicemia in Children. J Fatima Jinnah Med Univ [Internet]. 22Nov.2018 [cited 30Sep.2022];9(1). Available from: https://jfjmu.com/index.php/ojs/article/view/117