Frequency and Factors Associated with Persistent Otorrhea Following Modified Radical Mastoidectomy for Cholesteatoma in Adult Patients: A Retrospective Study

Authors

  • Shuman Roy Department of ENT, Akhtar Saeed Trust Hospital, Lahore, Pakistan
  • Mujahid Ali Department of ENT, Fatima Jinnah Medical University, Lahore
  • Amna Rafique Abbasi Department of ENT, Akhtar Saeed Trust Hospital, Lahore, Pakistan
  • Ali Husnain Sheikh Department of ENT, Akhtar Saeed Trust Hospital, Lahore, Pakistan
  • Werdah Zia Department of ENT, Rashid Latif Medical College, Lahore, Pakistan
  • Zubair Iqbal Bhutta Department of ENT, Rashid Latif Medical College, Lahore, Pakistan

DOI:

https://doi.org/10.37018/JQQE8943

Keywords:

Cholesteatoma, Modified Radical Mastoidectomy, Otorrhea, Mastoidectomy, Surgical Outcomes

Abstract

Background: Cholesteatoma is a destructive middle ear disease. Modified Radical Mastoidectomy (MRM) has proven to be a successful method for eradicating the disease however, there is some concern about the continued otorrhea (ear drainage) following surgery, and studies have shown inconsistent results internationally, with few local studies. Therefore, this study aimed to determine the frequency and associated factors of postoperative otorrhea following MRM in patients with cholesteatoma.
Methods: This retrospective analytical observational study was carried out in ENT department of Akhtar Saeed Trust Hospital, Lahore Pakistan from 1 July 2023 to 30 June 2024. A total of 109 patient records were reviewed and 16 were excluded due to previous ear surgery, intracranial complications, congenital cholesteatoma, incomplete records, and lack of follow-up. The Modified Radical Mastoidectomy operation was carried out on 93 adult (18-60 years) patients with cholesteatoma. Otoscopic examination and mucosalization, perforation of the tympanic membrane, high facial ridge, and meatal stenosis were evaluated at one month after surgery for signs of postoperative otorrhea. The data was analyzed using SPSS. 
Results: Among 93 patients, postoperative otorrhea was observed in 47 (50.5%) patients. Meatal stenosis was the most frequent contributing factor observed in 20 (42.5%) patients, followed by mucosalization in 10 (21.3%), tympanic membrane perforation in 10 (21.3%), and high facial ridge in 7 (14.9%) patients. Duration of disease greater than one year showed a significant association with postoperative otorrhea (p = 0.016).
Conclusion: Modified Radical Mastoidectomy for cholesteatoma is associated with a significant incidence of postoperative otorrhea. There were significant associations between postoperative otorrhea and female sex and longer duration of disease, but not between mucosalization, perforation of the tympanic membrane, high facial ridge, or meatal stenosis.

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Published

30.07.2026

How to Cite

1.
Frequency and Factors Associated with Persistent Otorrhea Following Modified Radical Mastoidectomy for Cholesteatoma in Adult Patients: A Retrospective Study. J Fatima Jinnah Med Univ [Internet]. 2026 Jul. 30 [cited 2026 Jul. 31];20(1):40-3. Available from: https://jfjmu.com/index.php/ojs/article/view/1445

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