Central Nervous System Tumours---- A Study of Frequency and Morphology

Authors

  • ROZINA JAFFAR TANYA DOGAR ASMAA QURESHY NAVID QURESH

Keywords:

central nervous system neoplasms

Abstract

Background: Owing to the confined space in the intra-cranial cavity,brain tumours even if benign can have life-threatening consequences. Malignant brain tumours can be widely invasive and infiltrative. Objective: To study the incidence, frequency and morphological patterns of CNS tumours. Method: A retrospective study of all cases of brain tumours received at Pathology Department PGMI was carried out from 1.1.2009 to 31.12.2010 . Results: A total of 96 cases of CNS tumours were studied during a period of two years.The morphological distribution was as follows : meningioma 18 (18.8%), glioblastoma multiforme 8 (8.3%), anaplastic astrocytoma 16 (16.7%), astrocytoma 12 (12.5%), pilocytic astrocytoma 2 (2.1%), oligodendroglioma 6 (6.3%), ependymoma 4 (4.2%), mixed glioma 4 (4.2%), schwannoma 8 (8.3%), craniopharyngioma 6 (6.3%), pituitary adenoma 6 (6.3%),haemangioblastoma 2 (2.1%) and metastases 4 (4.2%).64 cases (66.7%) occurred in males and 32 cases (33.3%) in females.80 (83.3%) patients were adults while 16 (16.7%) were children. Conclusion: CNS neoplasms are diverse in their morphology and grade.Histological examination of H&E stained sections enables diagnosis,classification and grading. In some cases, special stains and immunohistochemistry may be required. Correlation of histological examination with radiological findings ( CT and MRI ) and clinical data is essential.

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Published

2018-07-15

How to Cite

1.
TANYA DOGAR ASMAA QURESHY NAVID QURESH RJ. Central Nervous System Tumours---- A Study of Frequency and Morphology. J Fatima Jinnah Med Univ [Internet]. 2018 Jul. 15 [cited 2024 May 4];5(2). Available from: https://jfjmu.com/index.php/ojs/article/view/525

Issue

Vol. 5 No. 2 (2011): Journal of Fatima Jinnah Medical College

Section

Articles

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